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SALT LAKE CITY, Dec. 06, 2018 (GLOBE NEWSWIRE) — Countless Genetics, Inc. (MYGN), a baton in atomic affection and alone medicine, today appear after-effects from an important abstraction to validate the polygenic basic of a attainable riskScore™ analysis for Hispanic women who analysis abrogating for a ancestral blight alteration with the myRisk® Ancestral Blight test. The after-effects are actuality presented at the 2018 San Antonio Breast Blight Symposium (SABCS) in San Antonio, Texas.
“A year ago, we launched riskScore as a cogent accessory to myRisk® to accommodate women of European ancestor with added abiogenetic advice about their lifetime accident of developing breast cancer,” said Jerry Lanchbury, Ph.D., arch accurate officer, Countless Genetics. “This year we are aflame to presents after-effects from about 14,000 women which is the better polygenic abstraction anytime conducted for Hispanic ancestry. It is addition footfall in our charge to accomplish riskScore attainable to all women, including those best underrepresented in our bloom affliction system.”
The key abstracts actuality presented at SABCS are abbreviated below. Amuse appointment Countless at Booth #1001 to apprentice added about abiogenetic testing for breast cancer. Follow Countless on Twitter via @myriadgenetics and accumulate up to date with Symposium account and updates by application the hashtag #SABCS18.
Polygenic Account Poster Presentation Title: Development and Validation of a Polygenic Account to Adumbrate Breast Blight Accident in Artless Hispanic Women Abrogating for Mutations on a Multigene Ancestral Blight Panel.Presenter: Elisha Hughes, Ph.D.Date: Friday, Dec. 7, 2018, 5:00 – 6:00 p.m. Poster: P5-10-02
This abstraction evaluated 87 distinct nucleotide polymorphisms (SNPs) as breast blight accident factors through the validation of a polygenic account in 8,487 women of Hispanic ancestry. The after-effects appearance that the 87-SNP polygenic account was awful predictive of breast blight accident in artless Hispanic women with a cogent ancestors blight history who activated abrogating for germline mutations in accepted breast blight accident genes (p=7.1×10-19). Estimates of about accident due to SNPs ranged from 0.2 to 3.6 (Graph 1). The analytic accomplishing of riskScore for women of Hispanic ancestor may decidedly advance the administration of high-risk Hispanic women who analysis abrogating for mutations in with
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